Figure 1. Dependence of the Control Reproduction Number (Rc) on the average population-level testing frequency for HIV (in terms of years between tests) and the treatment initiation threshold in terms of the CD4 cells/µL.
The dotted black line represents the threshold Rc = 1; below this threshold (i.e., Rc<1) elimination is (theoretically) possible. Panels represent the average treatment-induced reduction in infectivity at the population level: (A) 96% (B) 90% (C) 85%.