Table 2.
Comparison of genotypes and demographic characteristics of mothers by use of supplements containing synthetic folic acid in the 1st trimester
| Used folic acid containing supplements in the first trimester | Did not use folic acid containing supplements in the first trimester | |
|---|---|---|
|
| ||
| n = 81 | n = 88 | |
|
| ||
| Characteristic | Proportion affected % (n affected/n total informative) | Proportion affected % (n affected/n total informative) |
|
| ||
| Homozygous for DHFR19bp del | 20.25 (16/79) | 20.45 (18/88) |
| Homozygous for MTHFR677C>T | 31.65 (25/79) | 21.84 (19/87) |
| Had child with unilateral retinoblastoma | 44.44 (36/81) | 41.91 (36/88) |
|
| ||
| Median (range) | Median (range) | |
|
| ||
| Age at delivery (years) | 25.6 (14.4, 39.5) | 24.5 (14.9, 39.5) |
| Years of schooling* | 9 (4,17) | 9 (0,17) |
*
p= 0.006, group mean difference detected by t-test.