Table 2.

Gene expression current study: Normalized copy number, ln transformed, mean and std dev for the 26 genes compared between shoulder and body wall implantation sites at 28 days.

GENE			28 Day Gene Expression
Category	Name	Abbr.	Shoulder Xenograft Mean (SD)	Body Wall Xenograft Mean (SD)
Pro-inflammatory	Interleukin-1α	IL-1α	−8.66(4.51)	−9.50(4.34)
	Interleukin-1β	IL-1β	−6.93(3.49)	−7.24(4.15)
	Interleukin-6	IL-6	−11.12(3.61)	−12.11(3.40)
	Interleukin-8	IL-8	−13.99(3.40)	−15.13(2.41)
	Interleukin-12β	IL-12β	−10.25(3.08)	−9.90(3.02)
	Interleukin-18	IL-18	−7.02(4.55)	−6.80(4.16)
	Interferon-γ	INFγ	−13.19(4.25)	−12.78(6.32)
	inducible Nitric Oxide Synthase	iNOS	−6.81(3.30)	−6.51(3.48)
	Tumor Necrosis Factor-α	TNFα	−10.13(4.86)	−9.73(2.58)
Pro-remodeling	Arginase	ARG	−13.96(3.12)	−14.11(3.07)
	Interleukin-1 receptor antagonist	IL-1ra	−5.52(2.86)	−4.85(3.64)
	Interleukin-4	IL-4	−12.83(4.11)	−12.97(4.29)
	Interleukin-5	IL-5	−18.21(4.80)	−17.06(3.87)
	Interleukin-10	IL-10	−12.18(3.23)	−12.24(2.86)
	Interleukin-13	IL-13	−13.00(3.32)	−12.58(3.40)
	Transforming Growth Factor-β	TGF-β	−6.89(3.54)	−7.01(2.83)
ECM/Tendon	Decorin	DEC	−3.40(3.96)	−3.50(3.87)
	Collagen Type I	Col I	1.18(3.72)	0.15(3.92)
	Collagen Type III	Col III	−8.09(3.84)	−7.95(3.35)
	Thrombospondin-4	TSP4	−11.42(3.27)	−11.27(3.12)
	Scleraxis	SCX	−10.36(3.99)	−11.54(4.36)
	Tenomodulin	TND	−7.51(5.20)	−8.44(5.30)
Enzyme	Cathepsin K	Cat K	−6.33(3.87)	−4.85(4.54)
	Matrix Metalloproteinase-2	MMP2	−10.37(4.26)	−10.55(4.49)
	Matrix Metalloproteinase-3	MMP3	−6.95(3.97)	−7.07(3.96)
	Matrix Metalloproteinase-13	MMP13	−5.59(2.93)	−5.74(3.81)