Table 5.
Clinical, Treatment, Neck Dissection Characteristics | GT1 Dependence at 12 Months | GT Dependence at 24 Months | ||
---|---|---|---|---|
p-value | OR2 (95% CI) | p-value | OR (95% CI) | |
Primary Tumor Site (Oropharyx vs. Other) | 0.52 | 0.7 (0.2 – 2.2) | 0.57 | 1.9 (0.2 – 16.2) |
T Stage (T1–T4) | 0.003 | 2.3 (1.3 – 3.9) | 0.03 | 2.2 (1.1 – 4.5) |
N Stage (N1, N2a, N2b, N2c, N3) | 0.08 | 1.5 (1.0 – 2.5) | 0.69 | 1.1 (0.6 – 2.2) |
Chemotherapy Technique (Induction vs. CRT3) | 0.35 | 1,7 (0.6 – 5.2) | 0.86 | 0.9 (0.2 – 3.8) |
Type of ND4 (RND5 vs. MRND6) | 0.77 | 0.8 (0.3 – 2.7) | 0.3 | 0.3 (0.04 – 2.7) |
Complications after ND: | ||||
At Least One Complication | 0.60 | 1.3 (0.5 – 3.6) | 0.4 | 1.8 (0.5 – 7.4) |
At Least One Wound Complication | 0.27 | 2.3 (0.5 – 10.4) | 0.27 | 2.3 (0.5 – 10.4) |
Time of ND (ND before or after 12 weeks after CRT) | 0.20 | 1.9 (0.7 – 5.2) | 0.04 | 4.6 (1.1 – 19.9) |
Weight Loss from Start of CRT (≥10% vs. <10%) | 0.34 | 0.6 (0.2 – 1.8) | 0.48 | 0.6 (0.1 – 2.5) |
Tracheotomy | 0.11 | 0.06 | (1.1, 25.2) |
Abbreviations:
GT= gastrostomy tube,
OR= odds ratio,
CRT= chemoradiotherapy,
ND= neck dissection,
RND=radical neck dissection,
MRND= modified radical neck dissection