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Concentration-response relationships for ATP analogues causing relaxation of the rabbit aorta (endothelial P2Y-purinoceptor). Ordinate axis shows % relaxaiion of the noradrenaline (1 μM)-induced contraction; abscissa axis shows -log concentration of applied agonist; 11b, 2-(6-cyanohexyl)thio-ATP (▲); 15, adenosine-N1-oxide-5′-triphosphate (△); 14, 8-(6-amino-hexylamino)-ATP (▽); 18, 5-fluoro-UTP (◆); 22, 3′-deoxy-3′-amino-ATP (▼). Each point is the mean of 2–4 determinations.
