Fig. (9).

(A) The modeled position of eIF5B (purple ribbon) relative to the 30S subunit in the E. coli 70S ribosome crystal structure (adapted from [75]). Blue and orange spheres represent hydroxylradical cleavage positions in 18S rRNA obtained from eIF5B domains II and III, respectively, mapped onto corresponding regions of 16S rRNA. Note that eIF5B domain 4 is in front of, but does not contact the small ribosomal subunit. (B) The modeled position of eIF5B (in surface representation, colored purple) on the E. coli 70S ribosome crystal structure (adapted from [75]).