Fig 2.

Schematic structure of Liar, homology alignments, and expression patterns. (A) Domain structure of human Liar, indicating the putative sequences of the NLS and NES motifs. (B) Sequence alignments between human, mouse, and rat proteins using Clustal X 2.0 software. The shaded spots indicate variations in amino acid sequences. The GLPGRA box indicates the P loop region missing in human Liar, while the box in the C terminus shows the peptide used for immunization resulting in the C54 Liar antibody. (C and D) Expression patterns of ANKRD54/Liar transcripts in human tissues (C) and haematopoietic cell lines (D), including primary peripheral blood mononuclear cells (PBMCs). Sk., skeletal.