Table 1.

Genes that are up- and downregulated in E9.5 KLF1^−/− versus WT yolk sac erythroid cells^a

AffyID	Entrez ID	Gene symbol	Expression summary for:		Fold change	P value
			WT	KLF1−/−
1419175_a_at	12231	Btn1a1	6.94	9.00	4.19	0.0000205
1449360_at	12984	Csf2rb2	6.49	8.22	3.33	0.0065116
1421811_at	21825	Thbs1	8.86	10.58	3.30	0.0041092
1434853_x_at	54484	Mkrn1	9.75	11.41	3.16	0.0046076
1449280_at	71690	Esm1	6.07	7.66	3.02	0.0000491
1460241_a_at	20454	St3gal5	6.41	8.00	3.00	0.0073785
1418480_at	57349	Ppbp	6.55	8.08	2.89	0.0000965
1456014_s_at	108101	Fermt3	8.98	10.48	2.84	0.0007647
1436905_x_at	16792	Laptm5	8.05	9.47	2.68	0.0076590
1455504_a_at	NA	NA	9.41	10.82	2.67	0.0023565
1460232_s_at	NA	NA	7.31	8.69	2.59	0.0008638
1451425_a_at	54484	Mkrn1	8.51	9.86	2.54	0.0026376
1418835_at	21664	Phlda1	8.86	10.19	2.51	0.0014728
1432004_a_at	13430	Dnm2	5.19	6.50	2.48	0.0041875
1424966_at	94346	Tmem40	6.31	7.56	2.36	0.0055598
1435386_at	22371	Vwf	5.52	6.76	2.35	0.0018190
1450852_s_at	14062	F2r	9.92	11.15	2.35	0.0043781
1416811_s_at	NA	NA	6.85	8.07	2.33	0.0018710
1418412_at	21987	Tpd52l1	6.73	7.93	2.30	0.0002513
1451263_a_at	11770	Fabp4	7.76	8.94	2.25	0.0006915
1423062_at	16009	Igfbp3	6.55	7.71	2.23	0.0004194
1448471_a_at	13024	Ctla2a	9.62	10.75	2.19	0.0097492
1437726_x_at	12260	C1qb	6.06	7.15	2.12	0.0018801
1448954_at	78593	Nrip3	6.17	7.22	2.07	0.0007463
1416488_at	12452	Ccng2	8.24	9.29	2.07	0.0004951
1448736_a_at	15452	Hprt	10.18	11.20	2.02	0.0023947
1450344_a_at	19218	Ptger3	6.15	7.15	1.99	0.0036792
1439259_x_at	105501	Abhd4	9.43	10.42	1.98	0.0006879
1422798_at	66797	Cntnap2	7.90	8.88	1.97	0.0058018
1426970_a_at	NA	NA	7.15	8.10	1.93	0.0043149
1422474_at	18578	Pde4b	6.97	7.91	1.92	0.0042260
1422977_at	14724	Gp1bb	6.23	7.15	1.90	0.0000247
1416882_at	67865	Rgs10	9.10	10.02	1.89	0.0006363
1452352_at	13025	Ctla2b	8.62	9.54	1.89	0.0079715
1451196_at	383295	Ypel5	7.97	8.89	1.89	0.0008458
1427168_a_at	12818	Col14a1	7.32	8.23	1.89	0.0012275
1434059_at	230088	B230312A22Rik	7.36	8.24	1.84	0.0034893
1451453_at	13143	Dapk2	6.85	7.72	1.83	0.0037859
1433593_at	383295	Ypel5	5.58	6.44	1.81	0.0011630
1420664_s_at	19124	Procr	9.01	9.86	1.81	0.0080605
1418435_at	54484	Mkrn1	7.99	8.80	1.76	0.0076558
1435275_at	333182	Cox6b2	6.90	7.71	1.76	0.0058952
1424923_at	20715	Serpina3g	6.99	7.79	1.74	0.0036619
1426454_at	11857	Arhgdib	8.86	9.65	1.73	0.0075277
1423319_at	15242	Hhex	7.72	8.51	1.73	0.0023488
1425158_at	57246	Tbx20	5.45	6.24	1.72	0.0095330
1448995_at	56744	Pf4	11.21	11.96	1.68	0.0064027
1422444_at	16403	Itga6	7.25	7.98	1.66	0.0019243
1438261_at	56222	Cited4	6.32	7.05	1.65	0.0002694
1415874_at	24063	Spry1	8.32	9.04	1.65	0.0005373
1415949_at	12876	Cpe	6.99	7.71	1.64	0.0009311
1423306_at	106878	2010002N04Rik	7.48	8.19	1.64	0.0016944
1417214_at	80718	Rab27b	5.42	6.11	1.61	0.0016003
1433964_s_at	108101	Fermt3	6.55	7.23	1.61	0.0065248
1419259_at	20163	Rsu1	10.12	10.79	1.60	0.0031843
1417023_a_at	11770	Fabp4	6.47	7.14	1.59	0.0037652
1426450_at	224860	Plcl2	7.69	8.34	1.57	0.0005064
1450016_at	12450	Ccng1	8.91	9.55	1.56	0.0059483
1448657_a_at	56812	Dnajb2	8.41	9.03	1.54	0.0031640
1452358_at	24004	Rai2	3.93	4.55	1.53	0.0000153
1427040_at	16543	Mdfic	8.38	8.98	1.52	0.0062468
1452366_at	234356	Csgalnact1	6.14	6.74	1.52	0.0073674
1448694_at	16476	Jun	6.84	7.43	1.50	0.0008474
1421268_at	22234	Ugcg	6.49	7.07	1.50	0.0062467
1434087_at	17769	Mthfr	6.96	7.54	1.50	0.0082196
1416315_at	105501	Abhd4	7.33	7.91	1.50	0.0065987
1417978_at	66892	Eif4e3	7.72	8.30	1.49	0.0018258
1423212_at	13619	Phc1	8.22	8.79	1.49	0.0074183
1455220_at	212398	Frat2	7.35	7.92	1.48	0.0019347
1421633_a_at	12950	Hapln1	5.95	6.51	1.47	0.0086383
1426734_at	224093	Fam43a	6.99	7.53	1.46	0.0063603
1417426_at	19073	Srgn	7.89	8.43	1.46	0.0098012
1419298_at	269823	Pon3	5.49	6.02	1.44	0.0032081
1418104_at	78593	Nrip3	5.32	5.83	1.43	0.0048456
1428794_at	432572	Specc1	7.03	7.54	1.42	0.0032746
1420124_s_at	102791	Tcta	7.39	7.90	1.42	0.0025608
1425570_at	27218	Slamf1	6.83	7.33	1.41	0.0089085
1415850_at	19414	Rasa3	7.01	7.50	1.40	0.0049996
1416714_at	15900	Irf8	5.98	6.46	1.40	0.0004215
1416843_at	18582	Pde6d	6.72	7.20	1.39	0.0057671
1431597_a_at	78593	Nrip3	4.44	4.90	1.38	0.0007931
1423286_at	12404	Cbln1	7.91	8.36	1.37	0.0053469
1425506_at	107589	Mylk	8.11	8.56	1.36	0.0066188
1448134_at	27355	X99384	7.79	8.24	1.36	0.0040177
1426624_a_at	66090	Ypel3	8.03	8.48	1.36	0.0098438
1418144_a_at	18720	Pip5k1a	7.39	7.82	1.36	0.0053209
1425125_at	18302	Oit3	6.72	7.16	1.35	0.0034544
1435383_x_at	17984	Ndn	11.13	11.57	1.35	0.0051937
1422699_at	11684	Alox12	5.37	5.80	1.35	0.0096007
1437401_at	16000	Igf1	6.44	6.86	1.34	0.0042858
1434555_at	11737	Anp32a	9.53	9.95	1.33	0.0032632
1435382_at	17984	Ndn	11.08	11.49	1.33	0.0087450
1449402_at	60322	Chst7	6.27	6.67	1.32	0.0037640
1422817_at	14729	Gp5	6.54	6.94	1.32	0.0072048
1436448_a_at	19224	Ptgs1	5.83	6.23	1.32	0.0032874
1437849_x_at	67416	Armcx2	9.95	10.35	1.32	0.0051815
1417363_at	22719	Zfp61	5.67	6.06	1.31	0.0090568
1455180_at	102371	Gcom1	5.55	5.93	1.31	0.0066221
1416935_at	22368	Trpv2	6.15	6.53	1.30	0.0057705
1427007_at	74131	Sash3	7.24	7.62	1.30	0.0070703
1417755_at	106021	Topors	5.54	5.88	1.27	0.0086579
1448024_at	18162	Npr3	6.12	6.46	1.27	0.0059614
1417523_at	56193	Plek	6.52	6.86	1.26	0.0014985
1448443_at	20713	Serpini1	5.44	5.75	1.24	0.0041357
1455367_at	213236	Dnd1	5.46	5.75	1.22	0.0050743
1428816_a_at	14461	Gata2	6.86	7.15	1.22	0.0071113
1427287_s_at	16439	Itpr2	5.18	5.44	1.20	0.0060864
1426604_at	24014	Rnasel	4.38	4.63	1.18	0.0096496
1450442_at	11519	Add2	7.44	7.11	−1.26	0.0046469
1422866_at	12817	Col13a1	6.77	6.43	−1.26	0.0015366
1455035_s_at	67134	Nop56	9.69	9.29	−1.32	0.0029171
1428390_at	72515	Wdr43	9.75	9.33	−1.33	0.0069107
1429080_at	67973	Mphosph10	9.02	8.60	−1.34	0.0017344
1419660_at	67008	1600012F09Rik	8.85	8.40	−1.36	0.0027637
1424021_at	65103	Arl6ip6	8.09	7.63	−1.37	0.0087204
1427954_at	270802	BC048403	4.82	4.36	−1.38	0.0095131
1420918_at	170755	Sgk3	6.97	6.51	−1.38	0.0061668
1417675_a_at	100019	Mdn1	7.68	7.17	−1.42	0.0098793
1449623_at	232223	Txnrd3	6.54	6.01	−1.45	0.0063133
1424437_s_at	192663	Abcg4	6.73	6.19	−1.45	0.0023347
1424858_at	217666	L2hgdh	7.48	6.91	−1.49	0.0063305
1424722_at	71775	1300017J02Rik	7.94	7.36	−1.49	0.0078258
1436990_s_at	NA	NA	10.46	9.85	−1.52	0.0045047
1460371_at	72630	Hspa12b	7.80	7.19	−1.53	0.0085880
1421883_at	15569	Elavl2	4.72	4.09	−1.55	0.0070508
1420339_at	76890	Memo1	8.46	7.82	−1.56	0.0019363
1434959_at	13363	Dhh	7.28	6.51	−1.71	0.0000812
1422920_at	57255	Cldn13	7.03	6.21	−1.76	0.0048145
1451229_at	232232	Hdac11	6.72	5.89	−1.78	0.0045228
1424117_at	414077	BC056474	7.03	6.18	−1.80	0.0052470
1449424_at	27260	Plek2	8.34	7.47	−1.83	0.0025433
1417092_at	19228	Pth1r	6.10	5.22	−1.84	0.0083709
1452324_at	19296	Pvt1	8.26	7.38	−1.84	0.0001237
1424942_a_at	17869	Myc	7.35	6.46	−1.85	0.0021150
1437614_x_at	224454	Zdhhc14	7.76	6.86	−1.87	0.0032367
1438975_x_at	224454	Zdhhc14	7.81	6.84	−1.95	0.0010981
1418591_at	58233	Dnaja4	7.58	6.59	−1.99	0.0014377
1432332_a_at	110959	Nudt19	8.25	7.19	−2.09	0.0009313
1448300_at	66447	Mgst3	9.75	8.68	−2.09	0.0023340
1460223_a_at	13829	Epb4.9	7.45	6.30	−2.22	0.0004694
1437502_x_at	12484	Cd24a	10.12	8.94	−2.27	0.0001713
1460444_at	109689	Arrb1	6.05	4.83	−2.33	0.0049112
1448182_a_at	12484	Cd24a	9.31	8.05	−2.40	0.0011112
1448530_at	66355	Gmpr	8.13	6.85	−2.42	0.0001778
1438619_x_at	224454	Zdhhc14	7.45	6.16	−2.44	0.0000852
1416034_at	12484	Cd24a	8.64	7.27	−2.59	0.0000683
1438711_at	18770	Pklr	8.63	7.21	−2.66	0.0000103
1451415_at	69068	1810011O10Rik	8.14	6.71	−2.68	0.0000060
1418600_at	16596	Klf1	10.67	9.15	−2.87	0.0013763
1452661_at	22042	Tfrc	11.40	9.87	−2.89	0.0017499
1456307_s_at	11513	Adcy7	8.62	7.02	−3.05	0.0000228
1422930_at	78369	Icam4	8.33	6.70	−3.09	0.0000331
1417184_s_at	NA	NA	11.67	9.97	−3.24	0.0011955
1435945_a_at	16534	Kcnn4	10.26	8.46	−3.48	0.0000054
1427866_x_at	15130	Hbb-b2	8.07	6.15	−3.79	0.0048748
1418909_at	27028	Ermap	10.17	8.11	−4.16	0.0013191
1420468_at	66772	Asb17	7.24	4.93	−4.96	0.0000063
1449077_at	170812	Ahsp	12.98	8.11	−29.35	0.0000000

^aMean probe set expression summaries for WT and KLF^−/− cells were calculated by RMA. Some genes were detected by multiple AffyID probe sets, and there are multiple entries for these genes. Positive n-fold values indicate genes that are upregulated in KLF1^−/− versus WT erythroid cells; negative n-fold values indicate genes downregulated in KLF1^−/− versus WT erythroid cells.