Table 2.
Increased expression of CD14 and CD32 but reduced expression of CD11b by H. pylori-infected M1 macrophages
| Treatmenta | Surface molecule expression (median MFI)b |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| CD11b | CD14 | CD16 | CD32 | CD64 | CD80 | CD86 | CD206 | HLA-DR | |
| H. pylori | 17* (9, 21) | 52* (26, 72) | 2 (1, 4) | 44* (38, 47) | 0 (0, 2) | 12 (1, 14) | 6 (4, 8) | 21 (0, 26) | 25 (21, 40) |
| LPS | 27 (13, 34) | 24 (18, 49) | 4 (2, 5) | 43 (37, 46) | 0 (0, 2) | 13* (3, 20) | 13 (9, 23) | 13 (0, 38) | 39 (30, 41) |
| Medium | 61 (11, 81) | 12 (8, 18) | 3 (1, 6) | 32 (28, 37) | 1 (0, 3) | 1 (0, 3) | 12 (8, 18) | 33 (0, 64) | 47 (43, 63) |
a
H. pylori, infected with H. pylori; LPS, stimulated with LPS; medium, treated with medium only.
b
Values are based on at least six independent experiments (six donors). MFIs of isotype controls were subtracted. Values in parentheses are the 25th and 75th percentile MFIs, respectively.
*
, P < 0.05 (Friedman test and Dunn's multiple comparison test).