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Impact of TCTP priming ex vivo on reactivity to anti-IgE challenge. After 15 min of preincubation (priming) with PBS or rTCTP (top, hTCTP; bottom, PfTCTP) at 1 μg/ml, blood samples were stimulated with anti-IgE (aIgE) at 1 μg/ml for 15 min. Modulation of the aIgE response due to TCTP priming is represented in percentages of inhibition or enhancement. Dashed and continuous lines represent ER and LR, respectively.
