Table 3.
Day | No. of mice colonized with wild type | No. of mice colonized with Δure | CIa |
P valueb | |
---|---|---|---|---|---|
Mean | Median | ||||
1 | 17 | 17 | 2.28 | 2.23 | 0.0002 |
2 | 17 | 17 | 3.38 | 2.33 | 0.0014 |
3 | 16 | 16 | 9.44 | 5.33 | <0.0001 |
4 | 15 | 15 | 99.52 | 7.25 | 0.0006 |
5 | 14 | 12 | 54.46 | 13.51 | 0.0005 |
6 | 14 | 11 | 389.1 | 11.70 | 0.002 |
7 | 14 | 10 | 139.9 | 12.98 | 0.0078 |
CI (competitive index) calculated as CFU per gram of feces for wild-type strain/Δure mutant. Mice for which colonization by the Δure mutant could no longer be detected are not included in this analysis.
P values were calculated using the Wilcoxon signed-rank test.