Fig. 6.

Acquisition of conditioning is inhibited by anti-tGluA4 or anti-GluA1 siRNA treatment and rescued by tGluA4 flop rescue plasmid. Percent of conditioned response (CR) acquisition after 1 and 2 pairing sessions for the different treatment groups is shown. Treated preparations were incubated in the siRNA alone followed by conditioning or pretreated with rescue plasmids followed by tGluA4 siRNA and the conditioning procedure. Physiological traces from some of these groups show representative recordings of CRs (arrows) and URs during paired stimulation. *Significant differences from Ps2; #significant differences from C2. CS, conditioned stimulus; US, unconditioned stimulus.