Table 1.
Astrocyte Group | RMP, mV | Gt, nS | Gm, nS | Cm, pF | tm, ms | n |
---|---|---|---|---|---|---|
A1 | ||||||
Uninfected | −69.2 ± 1.30 | 33.6 ± 1.64 | 168 ± 8 | 37.9 ± 2.16 | 1.05 ± 0.04 | 28 |
Day 3 PI | −73.3 ± 1.15a | 30.9 ± 1.26 | 154 ± 6 | 68.9 ± 6.95c | 2.22 ± 0.24c | 18 |
Day 7 PI | −67.2 ± 4.63 | 42.1 ± 5.44 | 210 ± 27 | 28.4 ± 3.08 | 0.91 ± 0.05b | 8 |
A2 | ||||||
Uninfected | −76.6 ± 1.12e | 21.1 ± 1.69e | 105 ± 8e | 29.3 ± 2.43d | 0.97 ± 0.05 | 21 |
Day 3 PI | −64.2 ± 1.61c,e | 29.9 ± 2.25b | 149 ± 11b | 66.7 ± 4.84c | 2.45 ± 0.28c | 15 |
Day 7 PI | −69.9 ± 1.71b | 21.3 ± 2.09e | 106 ± 10e | 34.6 ± 7.6 | 1.24 ± 0.19 | 14 |
Values are means ± SE. GFAP, glial fibrillary acidic protein; GFP, green fluorescent protein; PI, postinfection; RMP, resting membrane potential; Gt, total resting membrane conductance; Gm, estimated membrane conductance; Cm, cell membrane capacitance; tm, time constant.
P < 0.05;
P < 0.01,
P < 0.001 vs. uninfected slices;
P < 0.01,
P < 0.001 vs. A1 cells at same time point.