Fig. 2.
A minimal touch-evoked escape circuit is morphologically present in fakir mutants. A: lateral (left) and dorsal (right) schematics of the minimal touch-evoked escape circuit. HB, hindbrain; SC, spinal cord; PN, peripheral neurites; RB, Rohon-Beard cell; M cell, Mauthner cell; MN, motor neuron. B: immunohistochemical labeling of RB peripheral neurites innervating the skin (acetylated tubulin), RB cell bodies (Islet-1), Mauthner cells (3A10), motor axons (SV2), and nicotinic acetylcholine receptors (Alexa-594-conjugated α-bungarotoxin) highlighted by arrows in wt and far mutants. All images are lateral views with rostral to the left except for Mauthner cells, wherein the dagger denotes a dorsal view with rostral toward the top. Scale bar, 50 μm.
