Fig. 7.

Example of salicylate's effects on multiunit (MU) response to noise bursts across depth of A1. Top of each subpanel is a raster of spike times (each dot represents a spike) in response to 50 stimulus presentations (broadband noise burst at 70 dB SPL). Horizontal black line in each subplot represents duration of noise-burst stimulus. Bottom of each subpanel is a peristimulus time histogram (PSTH) of mean firing rates across 50 stimulus presentations. Depth from cortical surface of MU response is indicated to the side of each subpanel and corresponding layers are indicated on the left of the figure. A: baseline MU responses were greatest in granular and upper infragranular layers and typically exhibited onset and/or sustained response types. B: MU responses following salicylate were more responsive to the onset of the stimulus than baseline recordings. The supragranular layer that was relatively unresponsive during baseline recordings became responsive following salicylate.