Fig. 6.

Plot showing the expected quantitative error during concurrent SIL addition as a function of the relative peptide production and decay rates. The dotted line shows the theoretical function when the rate constant for peptide production, k_p, is greater than that for peptide decay, k_d. The circles show the expected error calculated for all peptides whose rate constants could be determined. Note, the scale of the x axis changes at k_p/k_d = 100 for better visualization of the data. The inset shows the distribution of the expected relative errors for the 24 detectable surrogate peptides.