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. Author manuscript; available in PMC: 2012 Sep 6.
Published in final edited form as: AIDS. 2012 Jan 2;26(1):77–86. doi: 10.1097/QAD.0b013e32834dcee9

Table 1.

Outcome measure definitions and data sources

Metric Definition Reference Data Sources Numerator Population Denominator Population
Timing of HIV diagnosis
Intertest interval Median number of months between the last negative and the first positive HIV test Helms, et al [2] Surveillance case reports, testing history questionnaires, One-on-One charts. NA All persons newly diagnosed with HIV in King County, 2005–2009
CD4 count at diagnosis Median CD4 count at the time of HIV diagnosis CDC [3] First CD4 count reported to surveillance within 6 months after HIV diagnosis, One-on-One charts. NA
Late HIV diagnosis Proportion of persons diagnosed with AIDS within one year of HIV diagnosis CDC [4] Surveillance case report forms, CD4 count reports Persons reported with an AIDS diagnosis or laboratory surveillance evidence of a CD4 count <200 or CD4 percentage <14% within 12 month of HIV diagnosis date
AIDS and death within one year of HIV diagnosis Proportion of persons who were diagnosed with AIDS and died in the first year after HIV diagnosis Death reports, death ascertainment Persons with AIDS diagnosis and date of death <12 months after HIV diagnosis date
Linkage to HIV care
Linkage to initial care Proportion of persons who completed a medical visit within 3 months after HIV diagnosis NHAS [8] Dates of CD4 and VL results reported to surveillance Persons with a CD4 or VL result reported ≤ 3 months after HIV diagnosis date
Linkage to sustained care Proportion of persons who linked to initial care and completed a second visit 3–9 months after linkage NA Persons with a CD4 or VL result reported ≤ 3 months after HIV diagnosis date and second CD4 or VL result reported ≤ 9 months after the first All persons newly diagnosed with HIV in King County, 2007–2008
Engagement in continuous HIV care
NHAS engagement in care Proportion of persons with ≥ 2 medical visits ≥ 3 months apart in a calendar year NHAS [8] and the US Health Resources and Services Administration [5] Dates of CD4 and VL results reported to surveillance Persons with ≥ 2 CD4 or VL results ≥ 3 months apart in 2009 (excluding those whose first CD4 or VL was reported in the second half of 2009) Persons with ≥ 1 laboratory result in 2009 (excluding those whose first CD4 or VL was reported in the second half of 2009)
Population-based engagement in care NA Persons with ≥ 2 CD4 or VL results ≥ 3 months apart in 2009 (excluding those whose first CD4 or VL was reported in the second half of 2009) All PLWHA presumed to reside in King County as of December 31, 2009a (excluding those whose first CD4 or VL was reported in the second half of 2009)
Virologic parameters
Population-level virologic suppression Proportion of persons with virologic suppression (HIV RNA <48 copies/mL) NHAS [8] Montaner, et al [6] VL results reported to surveillance Persons with undetectable VL at the time of last report Persons with ≥ 1 VL result reported in 2009
Mean community viral load Mean viral load in the population Das, et al [7] NA

Empty cells indicate that the data source, numerator definition or denominator definition is the same as the completed cell above

a

All persons known to have an HIV diagnosis in King County, regardless of their place of diagnosis, who were not known to have died or relocated

NA, not applicable; CDC, U.S. Centers for Disease Control and Prevention; NHAS, U.S. National HIV/AIDS Strategy; PLWHA, persons living with HIV/AIDS; VL, viral load (HIV RNA)