Fig. 1.
TMZ-resistant D54-R and U87-R cells. (a) Representative dishes from clonogenic assay of the four cells 14 days after TMZ treatment. (b) Clonogenic percentage survival of TMZ-sensitive (D54-S and U87-S) and TMZ-resistant (D54-R and U87-R) cells after rechallenge with TMZ. Each experiment was repeated three times and performed in triplicate. Columns, mean results from triplicate assay; bars, SD; *P < 0.05 and **P < 0.01