Fig 1.

Bortezomib–mismatched unrelated donor reduced-intensity conditioning hematopoietic stem-cell transplantation. (A) Sustained total donor chimerism at days 30, 100, and 180 after transplantation in patients initially engrafted and without evidence of disease relapse/progression. Triangles indicate patients without sustained donor engraftment (≥ 70% total donor cell chimerism). Of note, donor chimerism analysis was not mandated beyond day 100. (B) Cumulative incidence of nonrelapse mortality (NRM; with relapse/progression as a competing event) and relapse/progression (with death as a competing event). (C) Cumulative incidence of grade 2 to 4 acute graft-versus-host disease (aGVHD) and grade 3 to 4 aGVHD (with relapse/progression and death as competing events). (D) Cumulative incidence of chronic GVHD (cGVHD; with relapse/progression and death as competing events). (E) Overall and progression-free survival. (F) Overall survival for HLA-C mismatched and non–HLA-C mismatched transplantation.