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Effect of HSF binding decoy on apoptosis. A) Caspase 3 activity at 16h. B) DNA fragmentation at 19h. Graphs summarize 3 separate experiments with 9–15/group. C - control; HS - heat shock; HS/TNF - 1 h hs followed by TNF treatment; TNF/HS - 6 h TNF followed by 1 h hs. SCR - scrambled sequence decoy (i.e. nonfunctional). * p < 0.05 vs. all. # P < 0.05 vs. C. + p < 0.05 vs. respective decoy.
