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The comparative analysis of VH CDR3 sequences in CLL showed that they were clearly distinct, in terms of amino acid composition and VH CDR3 length, from those identified in MCL carrying the same IGHV genes: IGHV3-21 (A) and IGHV4-34 (B). The height of symbols within the stack indicates the relative frequency of each amino or nucleic acid at that position. Modified from Agathangelidis et al. 2012.47
