Table 4. Baseline characteristics of patient populations prior to data pooling.

	Proof-of-concept1		Utilization study		Pooled dataset
	n = 30	%	N = 77	%	n = 107	%
Age, mean±SD	36±18		37±19		36±19
Age, range (years)	6–67		6–72		6–72
Male/female ratio	1.7		1.3		1.4
Nutritional status
BMI2 (kg/m) mean±SD	18.8±3.4		18.6±3.6		18.6±3.5
Severe malnutrition (BMI<16.5)	8	26.6	18	23.4	26	24.3
Diagnostic findings
Trypanosomes in blood	30	100.0	72	93.5	102	95.3
Trypanosomes in CSF3	28	93.33	69	89.6	97	90.7
WBC4 count in CSF	92±57		78±64		82±62
Clinical manifestations
Headache	27	90.0	73	94.8	100	93.5
Fever (>37.5)	7	23.3	13	16.9	20	18.7
Oedema	6	20.0	25	32.5	31	29.0
Joint pains	29	96.7	76	98.7	105	98.1
Daytime sleep	24	80.0	63	81.8	87	81.3
Night time sleep	23	76.7	50	64.9	73	68.2
Abnormal movements	8	26.7	20	26.0	28	26.2
Walking difficulties	13	43.3	53	68.8	66	61.7
Time period of enrolment	Oct 06–May 07		Oct 07–Aug 08		Oct 06–Aug 08

Note:

¹no suramin pre-treatment;

²body mass index,

³cerebrospinal fluid,

⁴white blood cell.