Skip to main content
. 2012 Sep 6;8(9):e1002891. doi: 10.1371/journal.ppat.1002891

Table 1. Peptide designation and properties.

Peptide designation Sequencea Net charge Molecular mass (g/mole) Charge densityb Hydrophobicity (% AcN)c
K9L6 LKKLKKLLKKLKKKL-NH2 +10 1849.7 0.667 36.7
5D-K6L9 LKLLKKLLKKLLKLL-NH2 +7 1805.4 0.467 55.6
K6L9 KLLKKLLKKLLKLL-NH2 +7 1805.4 0.467 67.2
K5L7 KKLLKLLLKLLK-NH2 +6 1451.0 0.500 56.5
C8-K5L7 CH3(CH2)6CO-KKLLKLLLKLLK-NH2 +5 1564.0 0.416 61.4
LL-37 LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES-NH2 +7 4493.3 0.324 67.6
Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS-NH2 +4 2466.9 0.227 67.1
Polymyxin B C50H100N16O17S +5 1301.5 0.455 53.2
Colistin C52H98N16O13 +5 1155.5 0.455 ND
a

Underlined and bold amino acids are D-enantiomers. All linear peptides are amidated in their C-terminus.

b

Calculated by dividing the net charge by the total number of amino acids.

c

The peptides were eluted in 40 min using a linear gradient of acetonitrile (AcN) from 30 to 70% v/v in water containing TFA (0.05% v/v) on a C4 reverse analytical column.