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. 2012 Sep 6;8(9):e1002891. doi: 10.1371/journal.ppat.1002891

Table 2. Minimum inhibitory concentrations (MIC90) towards GBS strains mutated in various cell surface components.

WT ΔdltA ΔmprF Δlgt Δlsp ΔcpsD ΔsrtA
K9L6 25 25 ND ND ND ND
5D-K6L9 4.4 2.2 4.4 4.4 4.4 4.4
K6L9 35.5 17.7 17.7 17.7 35.5 35.5
K5L7 25 25 ND ND ND ND
C8-K5L7 3 3 ND ND ND ND
LL-37 >14.2 3.6 >14.2 >14.2 >14.2 >14.2
Magainin 2 >25.5 6.4 >25.5 >25.5 >25.5 >25.5
Polymyxin B 92.4 5.8 92.4 92.4 92.4 92.4
Colistin >221.6 13.9 >221.6 >221.6 >221.6 >221.6

The MIC (µM) of each antimicrobial peptide is an average of triplicate measurements performed by a dilution method in 96-well polypropylene microplate. Plates were incubated overnight at 37°C and were then read at OD600 nm for bacterial growth. The MICs90 was considered to be the peptide concentration that inhibited growth of 90% of the tested strains.