Figure 2. Comparison of survival by day (left panel) and cumulative mortality (right panel) between naïve and vaccinated rag1^−/− mutant zebrafish in Trial 2.

Asterisk indicates a significantly lower mortality rate in vaccinated rag1^−/− mutant zebrafish when compared to naïve rag1^−/− mutant zebrafish. Fish were vaccinated with RE33® an attenuated strain of E. ictaluri and 8 weeks later challenged by a secondary injection of virulent E. ictaluri. DPI = days post secondary exposure. Error bars indicate standard error of the mean, SEM, between tanks (n = 16).