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. 2012 Sep 6;8(9):e1002669. doi: 10.1371/journal.pcbi.1002669

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© 2012 Torres-Sosa et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Plots of the probability that a percentage q of the network attractors is conserved after a gene the knockout of one gene for critical networks constructed de novo (A) and the critical networks that result from the evolutionary process (B). The differently colored distributions in B correspond to populations that started in different dynamical regimes (as in Fig. 1). Note the high probability for the de novo networks to lose all their attractors by a gene knockout () which does not happen for the evolved networks ( in all cases). Conversely the probability to conserve all attractors is considerably larger for the latter than for the former ( and, respectively). These data were computed from populations of 1000 networks and 500 attractors per network.

Inline graphic — Plots of the probability that a percentage q of the network attractors is conserved after a gene the knockout of one gene for critical networks constructed de novo (A) and the critical networks that result from the evolutionary process (B). The differently colored distributions in B correspond to populations that started in different dynamical regimes (as in Fig. 1). Note the high probability for the de novo networks to lose all their attractors by a gene knockout () which does not happen for the evolved networks ( in all cases). Conversely the probability to conserve all attractors is considerably larger for the latter than for the former ( and, respectively). These data were computed from populations of 1000 networks and 500 attractors per network.