Table 2. Univariate and multivariate analyses of prognostic factors associated with overall survival.

Covariates	Univariate analyses			Multivariate analyses
	HR	95% CI	P	HR	95% CI	P
Age (≤53 vs. >53 years)	0.992	0.723–1.362	0.962
Sex (female vs. male)	0.927	0.667–1.289	0.654
Etiology (HBV vs. HCV)	1.124	0.762–1.658	0.554
Child-Pugh class (Class A vs. Class B)	1.190	0.796–1.779	0.397
Serum AFP (≤20 vs. >20 ng/mL)	1.297	0.944–1.780	0.109
Tumor size (≤2 vs. >2 cm )	1.693	1.225–2.339	0.001	1.486	1.069–2.067	0.018
Tumor number (single vs. multiple)	1.228	0.880–1.714	0.227
Vein invasiona(no vs. Yes)	1.609	1.150–2.251	0.006	1.400	0.996–1.96	0.053
Number of TACE sessions(multiple vs. single)	0.589	0.396–0.875	0.009	0.713	0.475–1.071	0.104
Serum YKL-40 (normal vs. elevated)	1.973	1.372–2.838	<0.001	1.809	1.259–2.601	0.001

^aEvaluated on imaging findings.

HBV, hepatitis B virus; HCV, hepatitis C virus; AFP, alpha-fetoprotein.