Table 2. k-means clustering of CaCx cases portraying purely integrated HPV16 genomes.

Serial number	Sample ID	ln(Viral Load) per 100 ng DNA	E7 CT(APOT-coupled-quantitative-RT-PCR)	Cluster	Distance from cluster centre
1	T330	4.8	37.53	1	2.108
2	T267	7.83	36.56	1	1.656
3	T259	6.86	39.11	1	1.198
4	T263	7.3	39.34	1	1.491
5	T261	7.48	36.02	1	1.987
6	T228	6.97	38.91	1	1.003
7	T326	17.71	33.65	2	2.817
8	T265	16.46	38.28	2	1.979
9	T156	18.97	35.07	2	2.355
10	T239	15.77	35.48	2	1.535
11	T233	15.18	38.52	2	2.818
12	T244	17.99	37.28	2	1.328
13	T328	17.66	15.18	3	3.996
14	T336	13.81	9.8	3	2.825
15	T345	9.28	12.7	3	5.445
16	T333	16.78	11.01	3	2.527
17	T344	16.07	13.68	3	1.81
18	T321	11.26	2.74	4	1.933
19	T327	7.45	2.08	4	1.933

Cluster 1 : samples with low viral load, low E7 expression; Cluster 2: samples with high viral load, low E7 expression; Cluster 3: samples with moderate viral load, moderate E7 expression; Cluster 4: samples with low to moderate viral load, high E7 expression.