Table 2. k-means clustering of CaCx cases portraying purely integrated HPV16 genomes.
Serial number | Sample ID | ln(Viral Load) per 100 ng DNA | E7 CT(APOT-coupled-quantitative-RT-PCR) | Cluster | Distance from cluster centre |
1 | T330 | 4.8 | 37.53 | 1 | 2.108 |
2 | T267 | 7.83 | 36.56 | 1 | 1.656 |
3 | T259 | 6.86 | 39.11 | 1 | 1.198 |
4 | T263 | 7.3 | 39.34 | 1 | 1.491 |
5 | T261 | 7.48 | 36.02 | 1 | 1.987 |
6 | T228 | 6.97 | 38.91 | 1 | 1.003 |
7 | T326 | 17.71 | 33.65 | 2 | 2.817 |
8 | T265 | 16.46 | 38.28 | 2 | 1.979 |
9 | T156 | 18.97 | 35.07 | 2 | 2.355 |
10 | T239 | 15.77 | 35.48 | 2 | 1.535 |
11 | T233 | 15.18 | 38.52 | 2 | 2.818 |
12 | T244 | 17.99 | 37.28 | 2 | 1.328 |
13 | T328 | 17.66 | 15.18 | 3 | 3.996 |
14 | T336 | 13.81 | 9.8 | 3 | 2.825 |
15 | T345 | 9.28 | 12.7 | 3 | 5.445 |
16 | T333 | 16.78 | 11.01 | 3 | 2.527 |
17 | T344 | 16.07 | 13.68 | 3 | 1.81 |
18 | T321 | 11.26 | 2.74 | 4 | 1.933 |
19 | T327 | 7.45 | 2.08 | 4 | 1.933 |
Cluster 1 : samples with low viral load, low E7 expression; Cluster 2: samples with high viral load, low E7 expression; Cluster 3: samples with moderate viral load, moderate E7 expression; Cluster 4: samples with low to moderate viral load, high E7 expression.