Table 1. Univariate and multivariate stepwise backwards linear regression analyses.
Univariate analysis | Multivariate analysis | |||||
Peak | Coeff. | 95% CI | p-value | Coeff. | 95% CI | p-value |
P1 | 0.035 | [−0.260–0.329] | 0.816 | NS | NS | NS |
P2–P6 | 0.024 | [0.012–0.035] | 0.000 | 0.016 | [0.004–0.029] | 0.010 |
P7–P20 | 0.038 | [−0.015–0.091] | 0.160 | NS | NS | NS |
P21–P26 | 0.018 | [0.005–0.031] | 0.007 | 0.013 | [0.0005–0.026] | 0.042 |
P27–P32 | 0.007 | [−0.112–0.126] | 0.907 | NS | NS | NS |
P33–P38 | 0.023 | [0.002–0.044] | 0.032 | NS | NS | NS |
P39–P46 | 0.021 | [−0.043–0.085] | 0.519 | NS | NS | NS |
P47–P49 | 0.094 | [0.023–0.165] | 0.010 | 0.076 | [0.009–0.143] | 0.028 |
P50–P58 | 0.024 | [−0.014–0.061] | 0.207 | NS | NS | NS |
P59–P62 | 0.018 | [−0.012–0.047] | 0.238 | NS | NS | NS |
The table shows the association between the ability of DBL4ε anti-sera to inhibit binding of VAR2CSA expressing infected erythrocytes to CSA and the level of antibodies to the individual peptides. Antibody reactivity to groups of DBL4ε peptides according to the reactivity shown in figure 2A. NS: Not Significant.