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. 2012 Sep 6;7(9):e43790. doi: 10.1371/journal.pone.0043790

Table 4. Median and mean IFN-γ measurements for QuantiFERON-TB Gold In-Tube tests performed on the same subjects in three labs.

Source n Nil TB TB Response
Median Mean Median Mean Median Mean
Lab1 (original) unstratified 97 0.07 0.10 0.27 4.11 0.15 4.01
Lab2 (original) unstratified 97 0.06 0.09 0.24 3.88 0.19 3.79
Lab3 (original) unstratified 97 0.07 0.11 0.40 5.92 0.26 5.81
Lab1 (reconciled)
Unstratified * 91 0.07 0.09 0.18 3.11 0.08 3.01
Concordant Positive 35 0.07 0.11 3.93 7.85 3.31 7.74
Concordant Negative§ 49 0.07 0.08 0.08 0.10 0.01 0.02
Lab2 (reconciled)
Unstratified * 91 0.06 0.09 0.16 2.91 0.09 2.83
Concordant Positive 35 0.07 0.11 4.47 7.37 4.23 7.26
Concordant Negative§ 49 0.06 0.07 0.08 0.09 0.01 0.02
Lab3 (reconciled)
Unstratified * 91 0.07 0.11 0.32 2.94 0.18 2.33
Concordant Positive 35 0.07 0.12 3.72 6.04 3.25 5.91
Concordant Negative§ 49 0.07 0.10 0.11 0.14 0.02 0.05

Nil = IFN-γ concentrations (IU/mL) in plasma from the Nil tube of the QuantiFERON-TB Gold In-Tube test (QFT-GIT); TB = IFN-γ concentrations (IU/mL) in plasma from the TB tube of QFT-GIT; TB Response = TB minus Nil.

*

Includes 7 subjects with discordant QFT-GIT interpretations.

Concordant positive among results from all 3 labs.

§

Concordant negative among results from all 3 labs.