Table 4. Median and mean IFN-γ measurements for QuantiFERON-TB Gold In-Tube tests performed on the same subjects in three labs.
Source | n | Nil | TB | TB Response | |||
Median | Mean | Median | Mean | Median | Mean | ||
Lab1 (original) unstratified | 97 | 0.07 | 0.10 | 0.27 | 4.11 | 0.15 | 4.01 |
Lab2 (original) unstratified | 97 | 0.06 | 0.09 | 0.24 | 3.88 | 0.19 | 3.79 |
Lab3 (original) unstratified | 97 | 0.07 | 0.11 | 0.40 | 5.92 | 0.26 | 5.81 |
Lab1 (reconciled) | |||||||
Unstratified * | 91 | 0.07 | 0.09 | 0.18 | 3.11 | 0.08 | 3.01 |
Concordant Positive† | 35 | 0.07 | 0.11 | 3.93 | 7.85 | 3.31 | 7.74 |
Concordant Negative§ | 49 | 0.07 | 0.08 | 0.08 | 0.10 | 0.01 | 0.02 |
Lab2 (reconciled) | |||||||
Unstratified * | 91 | 0.06 | 0.09 | 0.16 | 2.91 | 0.09 | 2.83 |
Concordant Positive† | 35 | 0.07 | 0.11 | 4.47 | 7.37 | 4.23 | 7.26 |
Concordant Negative§ | 49 | 0.06 | 0.07 | 0.08 | 0.09 | 0.01 | 0.02 |
Lab3 (reconciled) | |||||||
Unstratified * | 91 | 0.07 | 0.11 | 0.32 | 2.94 | 0.18 | 2.33 |
Concordant Positive† | 35 | 0.07 | 0.12 | 3.72 | 6.04 | 3.25 | 5.91 |
Concordant Negative§ | 49 | 0.07 | 0.10 | 0.11 | 0.14 | 0.02 | 0.05 |
Nil = IFN-γ concentrations (IU/mL) in plasma from the Nil tube of the QuantiFERON-TB Gold In-Tube test (QFT-GIT); TB = IFN-γ concentrations (IU/mL) in plasma from the TB tube of QFT-GIT; TB Response = TB minus Nil.
Includes 7 subjects with discordant QFT-GIT interpretations.
Concordant positive among results from all 3 labs.
Concordant negative among results from all 3 labs.