Table 2. Disease activity index.

Score*	Growth or weight loss	Diarrhea index
0	On par with non-DKO littermates	None
1	Growth arrest**
2	10% loss	Wet tail#
3	10% to 20% loss
4	≥20% loss¶	Diarrhea§

^*The final score is based on adding the results from the Growth and Diarrhea columns.

^**Cessation of growth commencing on day 8 to 13.

^#Matted and discolored fur at tail base. No accumulation of feces.

^¶Lethargy was not scored. It was taken into consideration to euthanize mice and occurred independent of scores.

^§Large accumulation of partially or completely dried stool at tail base.