Table 1. List of non-essential S. cerevisiae genes that when deleted significantly affect cytosolic redox state.
Mutant | Function | E GSH±SD (−mV) |
Wild type | – | 349±3 |
glr1 | Cytosolic/mitochondrial glutathione reductase | 275±4 |
yap1 | Oxidative stress responsive transcription factor | 319±4 |
skn7 | Oxidative stress responsive transcription factor | 320±5 |
dog2 | 2-deoxyglucose-6-phosphate phosphatase | 325±4 |
dig1 | MAP kinase-responsive inhibitor of the Ste12p | 327±6 |
dgr2 | Protein of unknown function | 330±4 |
dit1 | Sporulation-specific enzyme | 330±3 |
tkl1 | Transketolase | 330±4 |
ipk1 | Inositol 1,3,4,5,6-pentakisphosphate 2-kinase | 332±3 |
ysp1 | Mitochondrial protein | 332±4 |
nvj1 | Nuclear envelope protein | 332±3 |
rpl26b | Component of the large (60S) ribosomalsubunit | 332±6 |
inp2 | Peroxisome-specific receptor | 332±6 |
yju3 | Monoglyceride lipase | 332±5 |
ubi4 | Ubiquitin | 332±4 |
Mutants are listed from most to least oxidized.