Table 4. Genes annotated as “putative or unknown function” identified as contributing to cytosolic redox homeostasis in this study and their oxidative stress phenotype(s).

Gene	Phenotype	Reference
DOG2	Induced by oxidative stress	[20]
DGR2	Implicated in stress response signalling	[54]
RPI1	Inhibitor of Ras-cAMP pathway	[55]
PMP3	Increased glutathione excretion	[24]
HMS2	Predicted to regulated some responses to reducing conditions, heat shock and hydrogen peroxide.Homolog of SKN7	[56]
SVF1	Inhibits reactive oxygen species generation and promotes cell survival under oxidative stress conditions	[57]
ECM25	Increased glutathione secretion; decreased oxidative stress resistance	[24], [58]
ISF1	Similar to Mbr1p, a protein involved in mitochondrial function and stress responses	[59]