Table 1.

Expression levels of components of the non-neuronal cholinergic system in esophageal mucosa isolated from feline control versus idiopathic cystitis (FIC).

Enzymes	Control	Feline Interstitial Cystitis
ChAT	3.58 ± 1.65*	0.89 ± 0.08*
CarNT	112.50 ± 11.37	150.10 ± 20.29
AChE	24.01 ± 7.90	25.76 ± 4.12
Transporters
CHT	174.90 ± 36.65*	297.20 ± 32.59*
OCT-1	135.60 ± 39.04*	48.69 ± 5.26*
OCT-2	0.91 ± 0.25	0.84 ± 0.23
OCT-3	28.00 ± 4.72	21.42 ± 1.93
VAChT	30.41 ± 10.16*	71.17 ± 9.57*
VNUT	0.43 ± 0.21	0.23 ± 0.05
Adhesion molecule
Pan-cadherin	0.58 ± 0.15	0.29 ± 0.09
Receptors
M2	60.22 ± 18.80	62.54 ± 3.72
M3	4.60 ± 0.62	3.95 ± 0.33

^*P ≤ 0.05 (Student’s t test).