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. Author manuscript; available in PMC: 2013 Sep 28.
Published in final edited form as: Oncogene. 2012 Jun 4;32(13):1691–1701. doi: 10.1038/onc.2012.182

Figure 4. USP37 and p27 levels are correlated in human medulloblastoma and normal mouse cerebellum.

Figure 4

Figure 4

(A) Expression of USP37 (red) and p27 (green) in human medulloblastoma samples was assessed by IFA using specific antibodies and Cy3- or Alexa-488-conjugated secondary antibodies. Nuclei were stained with Hoechst dye and the images viewed and analyzed by fluorescence microscopy. (B and C) Distribution of p27 expression in USP37-expressing human medulloblastomas is provided. Significance and correlation were measured using the Wilcoxon rank-sum test and Spearman correlation test (rank correlation=0.67 and p<0.0001). (D) USP37 (red) and p27 (green) expression in cerebella of postnatal day 7 mice were evaluated by IFA as described above. EGL: external granule layer, IGL: Internal granule layer.