Table 2.

Correlation between years of schooling and regional cortical thicknesses and volumes after controlling for intracranial volume, age, gender, MMSE, and country of origin

	Control			MCI			AD
	r	p	q	r	p	q	r	p	q
Regional cortical thickness
Entorhinal cortex	0.108	0.266	0.488	0.085	0.367	0.732	−0.179	0.054	0.089
Parahippocampal gyrus	0.067	0.489	0.600	−0.033	0.723	0.821	−0.096	0.307	0.327
Middle temporal gyrus	0.165	0.088	0.348	0.161	0.084	0.682	−0.283	0.002	0.022a
Superior temporal gyrus	0.108	0.266	0.488	0.124	0.184	0.682	−0.262	0.005	0.041a
Inferior temporal gyrus	0.067	0.489	0.600	0.078	0.402	0.732	−0.237	0.010	0.046a
Temporal pole	0.165	0.088	0.348	−0.046	0.625	0.793	−0.190	0.041	0.087
Transverse temporal cortex	0.020	0.839	0.906	0.169	0.070	0.682	−0.156	0.094	0.124
Insula	0.067	0.491	0.600	0.061	0.517	0.732	−0.149	0.110	0.140
Fusiform gyrus	0.145	0.133	0.366	0.000	1.000	1.000	−0.227	0.014	0.046a
Medial orbitofrontal cortex	0.221	0.021	0.206	0.055	0.561	0.741	−0.165	0.077	0.110
Lateral orbitofrontal cortex	0.269	0.005	0.165	0.027	0.771	0.821	−0.144	0.122	0.146
Orbital operculum	0.215	0.025	0.206	0.124	0.184	0.682	−0.166	0.076	0.110
Frontal operculum	0.133	0.170	0.383	0.115	0.220	0.726	−0.183	0.050	0.087
Superior frontal gyrus	0.050	0.611	0.720	0.071	0.450	0.732	−0.208	0.025	0.069
Pars triangularis	0.151	0.119	0.357	0.070	0.453	0.732	−0.109	0.243	0.267
Frontal pole	0.162	0.095	0.348	0.029	0.753	0.821	−0.043	0.644	0.664
Rostral middle frontal gyrus	−0.007	0.939	0.952	0.146	0.117	0.682	−0.197	0.034	0.080
Caudal middle frontal gyrus	0.231	0.016	0.206	0.100	0.286	0.726	−0.234	0.012	0.046a
Precentral gyrus	0.075	0.443	0.600	0.124	0.186	0.682	−0.182	0.050	0.087
Superior parietal gyrus	0.162	0.093	0.348	0.036	0.704	0.821	−0.229	0.013	0.046a
Post central gyrus	0.154	0.111	0.357	0.190	0.041	0.682	−0.144	0.124	0.146
Paracentral gyrus	0.041	0.671	0.764	0.030	0.750	0.821	−0.188	0.044	0.087
Inferior parietal cortex	−0.074	0.444	0.600	0.075	0.423	0.732	−0.294	0.001	0.017a
Supramarginal gyrus	0.075	0.438	0.600	0.101	0.280	0.726	−0.185	0.047	0.087
Pericalcarine cortex	0.006	0.952	0.952	−0.178	0.056	0.682	−0.231	0.013	0.046a
Precuneus cortex	0.132	0.174	0.383	0.079	0.399	0.732	−0.230	0.013	0.046a
Lingual gyrus	0.104	0.286	0.4967	0.012	0.896	0.924	−0.159	0.087	0.120
Cuneus cortex	0.018	0.851	0.906	0.081	0.386	0.732	−0.214	0.021	0.063
Lateral occipital cortex	0.098	0.313	0.516	0.063	0.501	0.732	−0.297	0.001	0.017a
Isthmus of cingulate cortex	0.137	0.157	0.383	0.106	0.258	0.726	−0.173	0.064	0.101
Caudal anterior cingulate cortex	0.108	0.266	0.488	0.067	0.477	0.732	−0.021	0.820	0.820
Rostral anterior cingulate	0.067	0.489	0.600	0.059	0.532	0.732	−0.112	0.230	0.262
Posterior cingulate cortex	0.165	0.088	0.348	0.141	0.130	0.682	−0.203	0.029	0.074
Regional volume
Hippocampus	0.082	0.400	0.750	0.081	0.387	0.893	−0.095	0.312	0.736
Amygdala	0.034	0.727	0.839	0.052	0.576	0.893	−0.080	0.396	0.736
Caudate	−0.115	0.237	0.750	0.063	0.500	0.893	−0.038	0.686	0.736
Accumbens	0.090	0.355	0.750	0.073	0.433	0.893	−0.065	0.486	0.736
Putamen	−0.039	0.685	0.839	−0.013	0.893	0.893	−0.032	0.733	0.736
Pallidum	0.037	0.705	0.839	−0.143	0.124	0.893	−0.088	0.350	0.736
Brain stem	0.099	0.310	0.750	0.121	0.196	0.893	0.032	0.736	0.736
Cerebral cortex	0.051	0.601	0.839	0.024	0.797	0.893	−0.081	0.387	0.736
Cerebellum cortex	0.056	0.568	0.839	0.085	0.362	0.893	0.147	0.116	0.736
Thalamus	0.177	0.066	0.518	0.091	0.329	0.893	−0.034	0.721	0.736
Corpus callosum anterior	−0.115	0.235	0.750	0.029	0.760	0.893	−0.043	0.644	0.736
Corpus callosum central	−0.016	0.866	0.908	0.032	0.733	0.893	−0.041	0.665	0.736
Corpus callosum mid-anterior	0.176	0.069	0.518	0.138	0.140	0.893	−0.047	0.618	0.736
Corpus callosum mid-posterior	0.101	0.298	0.750	0.016	0.866	0.893	−0.052	0.581	0.736
Corpus callosum posterior	−0.011	0.908	0.908	−0.043	0.643	0.893	−0.062	0.506	0.736

^aIndicates significant correlation (false discovery rate < 0.05)