TABLE 1.
Asp289 (n = 29) | Glu298 (n = 30) | P between Genotypes | |
Female/male | 14/15 | 15/15 | |
Post-menopausal | 1 | 1 | |
Post-menopausal on HRT | 0 | 0 | |
Premenopausal taking OC | 9 | 9 | |
Caucasian ethnicity | 27 | 28 | |
Age (y) | 28.5 ± 2.4 | 28.4 ± 2.2 | 0.955 |
BMI (kg/m2) | 23.3 ± 0.7 | 23.2 ± 0.5 | 0.893 |
Systolic blood pressure (mmHg) | 124.9 ± 1.8 | 122.6 ± 1.6 | 0.347 |
Diastolic blood pressure (mmHg) | 76.8 ± 1.3 | 76.0 ± 1.7 | 0.694 |
TC (mmol/l) | 4.5 ± 0.2 | 4.6 ± 0.1 | 0.562 |
HDL-C (mmol/l) | 1.3 ± 0.1 | 1.6 ± 0.1 | 0.008 |
LDL-C (mmol/l) | 2.7 ± 0.1 | 2.5 ± 0.1 | 0.429 |
TAG (mmol/l) | 1.1 ± 0.1 | 1.1 ± 0.1 | 0.911 |
FMD (%) | 6.0 ± 0.7 | 5.4 ± 0.5 | 0.446 |
LDI-Ach AUC (AU) | 1520 ± 251 | 1225 ± 231 | 0.390 |
LDI-SNP AUC (AU) | 1506 ± 253 | 1025 ± 200 | 0.140 |
Bold text indicates significant P-values.