Table 1.
Clinical characteristics of the patients n (%)
| Clinical characteristics | Short course RT | Long course RT | Control | P1 |
| Study population (n = 214) | ||||
| Male | 57 (63) | 34 (64) | 32 (45) | 0.03 |
| Female | 33 (37) | 19 (36) | 39 (55) | |
| Mean age (yr) | 65.2 | 64.7 | 74.5 | < 0.001 |
| Preoperative T | ||||
| T1-2 | 28 (31) | 0 (0) | 22 (31) | |
| T3 | 54 (60) | 2 (4) | 12 (17) | < 0.001 |
| 2T4 | 1 (1) | 50 (94) | 3 (4) | |
| Tx | 7 (8) | 1 (2) | 34 (48) | |
| Postoperative T | ||||
| T1 | 3 (3) | 2 (4) | 5 (7) | |
| T2 | 34 (38) | 6 (11) | 26 (37) | |
| T3 | 50 (56) | 27 (51) | 37 (52) | < 0.001 |
| T4 | 3 (3) | 14 (26) | 3 (4) | |
| T0 | 0 | 4 (8) | 0 | |
| Postoperative N | ||||
| N0 | 53 (59) | 36 (68) | 41 (58) | |
| N1 | 26 (29) | 14 (26) | 15 (21) | 0.33 |
| N2 | 11 (12) | 3 (6) | 12 (17) | |
| Nx | 0 | 0 | 3 (4) | |
| Grade | ||||
| G1 | 9 (10) | 10 (19) | 12 (17) | |
| G2 | 58 (64) | 33 (62) | 48 (68) | 0.07 |
| G3 | 21 (23) | 3 (6) | 11 (16) | |
| Gx | 2 (2) | 7 (13) | 0 | |
| 3Crm (mm) | ||||
| 0 | 3 (4) | 11 (25) | 4 (9) | |
| 0 ≤ crm ≤ 2 | 9 (12) | 7 (16) | 7 (16) | 0.009 |
| > 2 | 65 (84) | 26 (59) | 32 (74) | |
| Disease specific outcome | ||||
| Alive without recurrence | 64 (71) | 25 (47) | 39 (55) | |
| Alive with recurrence | 7 (8) | 7 (13) | 4 (6) | 0.07 |
| Died of disease | 11 (12) | 12 (23) | 18 (25) | |
| Died of other causes | 8 (9) | 9 (17) | 10 (14) | |
1Differences between the three treatment groups using Fisher’s exact test; mean age with analysis of variance;
2
Includes the T3 tumors with threatened circumferential margin involvement;
3
Circumferential margin, data available in 164 cases. RT: Radiotherapy.