Table 1.
How often have you had the following symptoms: (GIS questionnaire) |
Before PPI therapy |
After PPI therapy |
P value | ||||||
Always | Often | Sometimes | Never | Always | Often | Sometimes | Never | ||
Pain in your chest or behind the breastbone? | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | NS |
Burning sensation in your chest or behind the breastbone? | 10 | 4 | 1 | 0 | 3 | 1 | 1 | 10 | < 0.05 |
Regurgitation or acid taste in your mouth? | 2 | 5 | 2 | 0 | 1 | 1 | 3 | 4 | < 0.05 |
Pain or burning in your upper stomach? | 1 | 2 | 2 | 0 | 0 | 1 | 1 | 3 | < 0.05 |
Sore throat or hoarseness that is related to your heartburn or acid reflux? | 27 | 5 | 9 | 0 | 23 | 8 | 6 | 4 | NS |
NS: Not statistically significant; GIS: Gastroesophageal reflux disease impact scale; PPI: Proton pump inhibitor.