Fig. 2.
Reduced Irk2 function wing phenotypes. (A) Quantification of wing defects when irk2 function is decreased (n≥100 flies). Error bars indicate s.e.m. (B) Bifurcation of L2 and L3 wing veins from Irk2DfA/Irk2DfB female. (C) Reduced wing size, angled hinge and bifurcation from L4 of Irk2DfA/Irk2DfB female. (D) Bristle transformations and incomplete L5 from male irk2G8696. (E) Wild-type male wing L2-5 longitudinal veins; anterior (a) and posterior (p) crossveins are labeled. (F) irk2DfA/irk2DfB male fly wing. (G) Wing expansion defects from daughterless-GAL4 Irk2 siRNA female. (H) Ubiquitous expression of irk2 siRNA causes patches of wing tissue necrosis. (I) Small wing and hinge defects from MS1096-GAL4 Irk2 siRNA female. (J) Small wing, hinge and venation defects from MS1096-GAL4 Irk2 siRNA male. (K) Rescued male irk2DfA/irk2DfB; engrailed-GAL4 UAS-irk2WT fly wing. Arrows indicate wing hinge defects. Scale bars: 100 μm.