Fig. 3. Treatment of HCV-infected chimpanzees with SPC3649 was well tolerated.
(A) Plasma trough levels of SPC3649, (B) alanine aminotransferase (ALT) levels and (C) Creatinine levels in HCV-infected chimpanzees during the study. (DāF) Photomicrographs of hematoxylin and eosin stained sections from biopsies of (D) a normal chimpanzee liver, (E) the animal 4Ć0513 at week ā4, (F) week 19, and (G) week 25, respectively.