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. 2012 Jul 10;287(35):29899–29908. doi: 10.1074/jbc.M112.391243

FIGURE 7.

FIGURE 7.

A simplified model of the interactions of miR-125b and its target genes in the context of cutaneous SCC. The down-regulation of miR-125b contributes to the increased expression of MMP13 (a direct target of miR-125b), MMP7 and MAP2K7 in cSCC cells, which promotes proliferation, migration, and invasion of cSCC cells.

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