FIGURE 7.

CD spectra of synthetic fusion peptides in POPG:POPG SUVs. A, shown are CD spectra of wild-type Hendra F fusion peptides in the presence or absence of SUVs composed of differing POPC:POPG ratios. B and C, CD spectra of wild-type and mutant Hendra F fusion peptides in the absence (B) or presence (C) of POPC:POPG 95:5 SUVs are shown. Spectra were obtained using a peptide concentration of 100 μm in solution or with 5 mm SUVs composed of POPC 100% or POPC:POPG 98:2, 95:5, and 92:8. All spectra were recorded at 22 ± 2 °C in a 0.5-mm quartz cuvette. Spectra were obtained from two independent sets of SUVs where each spectrum is an average of five scans.