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. 2012 Jul 2;287(35):29968–29978. doi: 10.1074/jbc.M112.379396

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© 2012 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 2. — SPDEF expression in PC3-Luc cells reduces tumor metastasis. A and B, representative images of bioluminescent images of mice injected with VC-Luc (n = 7) and SPDEF OE-Luc (n = 5) cells (n represents each model). Representative mice are shown. Shown are images at week 1 and week 12 post injection. C and D, quantitation of luciferase signal in the mice at the various time points shown. A significant decrease in disseminated tumor cells (luciferase activity) were detected in the SPDEF OE-Luc cells compared with the VC-Luc cells at 12 weeks. VC-Luc, VC-PC3-Luc; SPDEF OE-Luc, SPDEF-PC3-Luc. *, statistical significance (p < 0.05) compared with VC-Luc cells at 12 weeks.