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CXCR7 RNAi-knockdown downregulates mMMP-3 in 4T1 mouse mammary cancer cells. A total of 1 million 4T1-WT or 4T1-CXCR7-RNAi-985 cells were cultured in vitro for the indicated times. mMMP-3 levels in the conditioned media were determined by ELISA. The mean ± SEM is shown for triplicate wells. *p<0.05, Student's t-test.
