Table I.
Relationship between clinicopathological features and NGALR and/or NGAL positivity.
| Parameters | NGALR | NGAL | NGAL/NGALR | |||
|---|---|---|---|---|---|---|
|
|
|
|
||||
| % positive rate | P-value | % positive rate | P-value | % positive ratea | P-value | |
| Mean age, years (range) | ||||||
| <57 (46) | 39.1 (18/46) | 0.587 | 30.4 (14/46) | 0.684 | 19.6 (9/46) | 0.825 |
| ≥57 (56) | 33.9 (19/56) | 26.8 (15/56) | 17.9 (10/56) | |||
| Gender | ||||||
| Male | 30.2 (16/53) | 0.184 | 22.4 (11/49) | 0.198 | 17.0 (9/53) | 0.675 |
| Female | 42.9 (21/49) | 34.0 (18/53) | 20.4 (10/49) | |||
| Regional lymph node | ||||||
| N0 | 28.8 (15/52) | 0.112 | 25.0 (13/52) | 0.593 | 13.5 (7/52) | 0.172 |
| N1 | 44.0 (22/50) | 32.0 (16/50) | 24.0 (12/50) | |||
| Primary tumour | ||||||
| T1/T2 | 10.5 (2/19) | 0.018 | 10.5 (2/19) | 0. 026 | 5.3 (1/19) | 0.049 |
| T3 | 38.3 (23/60) | 26.6 (16/60) | 16.7 (10/60) | |||
| T4 | 52.2 (12/23) | 47.8 (11/23) | 34.8 (8/23) | |||
| Histopathology | ||||||
| Well-differentiated | 22.7 (5/22) | 0.193 | 9.1 (2/22) | 0.057 | 0 (0/22) | 0.004 |
| Moderately differentiated | 38.0 (27/71) | 32.4 (23/71) | 21.3 (15/71) | |||
| Poorly differentiated | 55.6 (5/9) | 44.4 (4/9) | 44.4 (4/9) | |||
| TNM stages | ||||||
| I/Пa | 23.7 (9/38) | 0.042 | 23.7 (9/38) | 0.413 | 7.9 (3/38) | 0.032 |
| Пb/Ш/IV | 43.6 (28/64) | 31.3 (20/64) | 25.0 (16/64) | |||
| Colorectal cancer | 36.3 (37/102) | 0.000 | 28.4 (29/102) | 0.000 | ||
| Normal mucosa | 8.6 (8/93) | 0 (0/81) | ||||
a
Positive, both NGAL and NGALR were positive in one case.
Positive rate, positive cases in the proportion of the overall.