FIGURE 5.

Effect of inhibiting mitochondrial function on myofiber healing. Myofibers isolated from EDL muscle were injured using a high intensity pulsed laser in the presence of 2 μm FM1-43 dye. The myofibers were either not treated (A) or treated with 10 μm CCCP for 30 min prior to injury (B). C, plot showing the kinetics of increase in FM1-43 intensity (arbitrary units (a.u.)) following injury averaged for up to 10 myofibers in each condition. The error bars define the S.E. in the signal at each time point.