Table I.
Genotypic variant | Control | Cancer | OR | 95% CI | P-value | ||
---|---|---|---|---|---|---|---|
|
|
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n | % | n | % | ||||
CYP1A1 | |||||||
wt/wt | 75 | 60.48 | 22 | 45.83 | 1.00 | ||
wt/m1 | 36 | 29.03 | 22 | 45.83 | 2.08 | 1.00–4.29 | 0.0422 |
m1/m1 | 13 | 10.48 | 4 | 8.33 | 1.04 | 0.30–3.56 | 0.9389 |
Allelic variant | |||||||
wt | 186 | 75.00 | 66 | 68.70 | 1.00 | ||
m1 | 62 | 25.00 | 30 | 31.30 | 1.36 | 0.77–2.35 | 0.2401 |
GSTM1 | |||||||
Positive | 100 | 80.65 | 24 | 50.00 | 1.00 | ||
Null | 24 | 19.35 | 24 | 50.00 | 4.16 | 1.95–8.89 | 0.0001 |
Smoking | |||||||
No | 60 | 48.39 | 7 | 14.58 | 1.00 | ||
Yes | 64 | 51.61 | 41 | 85.42 | 5.49 | 2.17–13.83 | <0.0001 |
OR, odds ratio; CI, confidence interval; wt, wild-type.