Of the 65 DLEC1 methylated cases, 37 patients succumbed to the disease (mean survival, 62.4 months). Of the 51 unmethylated cases, 18 patients succumbed to the disease (mean survival, 51.1 months). Thus, patients with DLEC1 methylated cancer were significantly associated with poor survival (log-rank test, p=0.0407). Black ovals, unmethylated cases; white ovals, methylated cases.