Table III.

Incidences and multiplicities of lung and liver proliferative lesions in A/J mice fed diets containing MeIQx and/or high fat.

			Adenoma + carcinoma		Lung proliferative lesiona		Liver adenoma
Group	Treatment	No.b	Incidence (%)c	Tumors/moused	Incidence (%)	Tumors/mouse	Incidence (%)	Tumors/mouse
1	MeIQx + high-fat diet	20	12/20 (60.0)e	0.90±0.85e	18/20 (90.0)f	1.85±1.27f	0/20 (0.0)	0
2	MeIQx	20	15/20 (75.0)g	1.45±1.23h	17/20 (85.0)i	1.90±1.45j	1/20 (5.0)	0.05±0.22
3	High-fat diet	18	4/18 (22.2)	0.33±0.69	6/18 (33.3)	0.50±0.86	0/18 (0.0)	0
4	Basal diet	19	6/19 (31.6)	0.32±0.48	6/19 (31.6)	0.32±0.48	0/19 (0.0)	0

^aHyperplasia + adenoma + carcinoma.

^bNumber of mice examined.

^cNumber of mice observed for each lesion (%).

^dMean ± SD.

^eSignificantly different from group 3 (P<0.05);

^fsignificantly different from group 3 (P<0.001);

^gsignificantly different from group 4 (P<0.05);

^hsignificantly different from group 4 (P<0.001);

ⁱsignificantly different from group 4 (P<0.01);

^jsignificantly different from group 4 (P<0.0001).